Pathogenic and protective roles of cytokines in pemphigus: a systematic review

S Tavakolpour, HR Mahmoudi, A Mirzazadeh, K Balighi… - Cytokine, 2020 - Elsevier
Pemphigus is a rare and life-threatening group of blistering … IL-1 and IL-8 are other mediators
involved in inflammation. … of pemphigus, some of the suggested targets include IL-4, IL-6, IL-…

[HTML][HTML] Analysis of serum cytokine profile in pemphigus

SH Lee, WJ Hong, SC Kim - Annals of dermatology, 2017 - ncbi.nlm.nih.gov
… of blisters in pemphigus, and many immunological steps are … mediators in serum, perilesional
skin, and blister fluid of … With our result further supporting the hypothesis, IL-6 seems to …

[HTML][HTML] Regulatory T cells suppress inflammation and blistering in pemphigoid diseases

K Bieber, S Sun, M Witte, A Kasprick… - Frontiers in …, 2017 - frontiersin.org
… CD62L shedding after 45 min of incubation and a decrease in IL-6, IL-8, and TNF-α production
… are pemphigoid diseases (PDs). Here, skin inflammation and subepidermal blistering are …

[HTML][HTML] Proinflammatory cytokine gene polymorphisms in bullous pemphigoid

PS Tabatabaei-Panah, H Moravvej, Z Sadaf… - Frontiers in …, 2019 - frontiersin.org
… Bullous pemphigoid (BP) is a rare autoimmune skin blistering disease, characterized by the
… cytokine and acts as a central and multifunctional mediator of diverse cellular events (12). IL-…

The Role of Proinflammatory Cytokines and the Inflammasome in Pemphigus

RA Eichkorn - 2023 - ub01.uni-tuebingen.de
… ) and interleukin-6 (IL-6) were detected in blister fluids and sera of … Besides having many
functions in the mediation of … at the desmosomes, a process called acantholysis 197. Two vital …

[HTML][HTML] Blister fluid induces MMP-9-associated M2-type macrophages in bullous pemphigoid

M Riani, C Muller, C Bour, P Bernard… - Frontiers in …, 2019 - frontiersin.org
… , their role in the blister formation process still needs to be … Inflammatory key mediators
secreted by these latter cells induce … Opposite behavior of TNF-alpha, interleukin-4 and interleukin…

The pathogeneses of pemphigus and pemphigoid diseases

H Ujiie, J Yamagami, H Takahashi, K Izumi… - Journal of …, 2021 - Elsevier
… key molecules that are relevant to blister formation may expand our … As is C5a, the lipid
mediator leukotriene B4 (LTB4) is a … By contrast, the proinflammatory cytokine IL-6 plays an anti-…

Distinct compartmentalization of immune cells and mediators characterizes bullous pemphigoid disease

C Margaroli, B Bradley, C Thompson… - Experimental …, 2020 - Wiley Online Library
… Bullous pemphigoid (BP) is an autoimmune blistering disease … Among markers of inflammation
measured in this study, IL-6, … differential recruitment process promoting blister formation. …

The role of sleep in pemphigus: a review of mechanisms and perspectives

MN Pedroni, C Hirotsu, AM Porro, S Tufik… - Archives of …, 2017 - Springer
… development of blisters and erosions on the skin and/or mucosa. Its inflammatory process is
mediated … Also, IL-6 serum concentrations were high both in active and remission stages of …

Biomarkers related to bullous pemphigoid activity and outcome

D Giusti, S Le Jan, G Gatouillat… - Experimental …, 2017 - Wiley Online Library
… BP-associated pathophysiological processes during the last … eosinophils released mediators
involved in blister formation. In … Although blister fluids displayed high level of IL-6, IL-17, IL-…